EPD (Enzyme Potentiated Desensitisation)

EPD (Enzyme Potentiated Desensitisation) was first used in the early 1960s by Doctor Leonard M. McEwen, a qualified medical doctor.  He found that an injection containing a single dose of grass pollen with a very small amount of beta glucuronidase (an enzyme produced naturally by the body) could be more effective in treating hay fever than a long course of conventional desensitising injections or courses of antihistamines. The enzyme appears to potentiate the allergen allowing a much smaller, and therefore safer, dose to be used.

The treatment normally consists of a series of injections into the skin initially at two month intervals. It takes about four weeks before any effect is seen.

EPD has been shown to be most effective for hayfever, food allergy and intolerance. It is also being investigated for the treatment of a wide range of conditions including asthma, rhinitis, Crohn’s disease, rheumatoid arthritis, eczema, urticaria, irritable bowel syndrome (IBS), migraine, chemical sensitivity, petit mal epilepsy, lupus, hyperactivity, ADD, ADHD, glue ear, neutropenia and psychological reactions such as depression and aggression.

EPD is still considered experimental by some doctors and allergists. However, there is a solid evidence base to support the effectiveness of the treatment in hayfever and related conditions. A total of nine well constructed clinical trials involving 271 patients showed a statistically significant improvement in symptoms.  With regard to safety, there have been no serious complications reported since it was first used.

Dr S Ahmed
Somerset Surgery
Hanley
Stoke On Trent
Staffordshire  ST1 2BH

Telephone:      01782 212192
Fax:                 01782 205078

Dr David Freed
14 Marston Road
Salford
Greater Manchester
Lancashire  M7 4ER

Telephone:      0161 795 6225
Fax:                 0161 795 6225

Dr Damien Downing
Nutritional Associates Ltd
Galtres House
Lysander Close
Clifton Moorgate
York
North Yorkshire  YO30 4XB

Telephone:      01904 691591
Fax:                 01904 690588

Dr Shena Roper
Sheffield Clinic of Complementary Medicine
378 Ecclesall Road
Sheffield
South Yorkshire  S11 8PJ

Telephone:      0114 268 0236
Fax:                 0114 267 9400

Dr Nicola Hembry
Greenway Community Practice
Greystoke Avenue
Bristol  BS19 6AF

Telephone:      0117 969 2814
Fax:                 0117 969 4253

Dr Chris Dawkins
The Breakspeare Clinic
Shipton Road
Milton Under Wychwood
Oxfordshire  OX7 6JP

Telephone:      01993 830913
Fax:                 01993 830086

Dr R Nicholson
Centre for Balanced Medicine
Western House
Fore Street
Chudleigh
Newton Abbot
Devon  TQ13 0HY

Telephone:      01626 854743
Fax:                 01626 853927

Dr Apelles Econs
Thames Allergy Centre
Marlborough House
68 High Street
Weybridge
Surrey  KT13 8BL

Telephone:      01932 820578
Fax:                 01932 830145

Also At:

Airedale Allergy Centre
41 Devonshire Street
Keighley
West Yorkshire  BD21 2BH

Oxford Allergy Centre
Raleigh Park Clinic
Raleigh Park Road
Oxford 
Oxfordshire  OX2 9AR

Patients should contact Weybridge for all centres.

Dr Michael Radcliffe

Patients should contact:
Sarum Road Hospital
Sarum Road
Winchester
Hampshire  SO22 5HA

Telephone:      01962 826127

Dr J N Thompson
39 Burroway Road
Langley
Berkshire  SL1 2PX

Telephone:      01753 775545
Fax:                 01753 775565

Dr Franziska Meuschel
The Diagnostic Clinic
50 New Cavendish Street
London  W1G 8TL

Telephone:      020 7009 4650
Fax:                 020 7009 4671

Royal London Homeopathic Hospital (NHS)
60 Great Ormond Street
London  WC1N 3HR

Telephone:      0207 391 8888
Fax:                 0207 391 8869

Doctors at RLHH currently using EPD:

Dr Saul Berkovitz
Dr S Z Haider
Dr Anton Van Rhijne
Dr Helmmut Roniger
Dr Andrea Weissner

EIRE AND NORTHERN IRELAND

Dr Joe FitzGibbon
Suite 31
The Galway Clinic
Doughiska
Galway
Ireland

Telephone:      00353 9172 0155
Fax:                 00353 9172 0156

Also At:

Suite 21
The Hermitage Clinic
Old Lucan Road
Dublin 20
Ireland

Patients should contact Galway for both centres.

Dr Mary McDermott
300 Cregagh Road
Belfast  BT6 9EW

Telephone:      028 9070 9300
Fax:                 028 9070 9309

WALES

Dr Sarah Myhill
Upper Weston
Llangunllo
Knighton
Powys  LD7 1SL

Telephone:      01547 550331
Fax:                 01547 550339

Page created: 16 June 2009